Welcome to the Tran Laboratory
Who are we!
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Join the team! |
Our Research!MicroRNAs are tiny molecules that circulate in our bodies. We discovered that when one these microRNAs is disrupted this change in expression can be measured in the blood. This can provide us with valuable clinical information about a patient’s susceptibility to oral cancer. |
Team PhotosWe currently have lab members working on various aspects of oral cancer research. We are serious about the work, but also find the time to have fun and enjoy our science!
Every year we also fund raise for the Cancer Council of NSW |
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Quantitative PCR Workshop - 4 Day Course
Our workshop will not be running in 2020 due to COVID19 and will be back in Jan 2021
Our 2019 workshop caters for beginners and also post-doctoral scientists wishing to further their understanding of qPCR. The course will cover experimental design, controls, and how to interpret your data. Hands-on experience will include cDNA preps, Sybr green, Taqman qPCRs, singleplex vs multiplex reactions.
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For 2019, we will also have practicals on designing mRNA and miRNA primer sets. Cost for the course is $400 (Inc GST+Booking Fee*) per person. Class size will be limited to 30 participants and includes all materials.
In 2020, we hope to deliver two course for PhD students and a more advance course for industry. Please register your interest with Fiona Deutsch (Fiona.Deutsch@student.uts.edu.au) |
Explainer: microRNA, the puppet master of the genomeWhat are miRNA? MicroRNAs, are very small ncRNAs found in cells and only represent less than 0.1% of the entire mammalian transcriptome. However these tiny RNAs can control up to two thirds of gene expression in mammalian cells. Many miRNAs are dysregulated in common cancers such as those originating in the breast, lung, colon, liver, head and neck and the prostate. They are now regarded as key regulators in the process of tumourigenesis and given their impact on tumour biology, a plethora of studies have also suggested the use of miRNAs as potential biomarkers. Our lab is using miRNAs to act as diagnostic or prognostic markers in head and neck cancers. |
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Our lab is part of The Translational Cancer Research Network (TCRN).
This group is a collaborative and interactive cancer research community based in the South East of Sydney, with links to cancer services and researchers in inner and southern Sydney, and Albury. It was formed to create an innovative and supportive environment for the translation of cancer research into improvements in patient care. Vertical Divider
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